Saccharomyces cerevisiae (R64-1-1)
Description

Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation [Source:SGD;Acc:S000001049]

Synonyms

CYP51

Location

Chromosome VIII: 120,091-121,683 reverse strand.

R64-1-1:BK006934.2

About this gene

This gene has 1 transcript (splice variant), 296 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
ERG11YHR007C_mRNA1593530aaYHR007C
 
Protein coding
P10614 NM_001179137.1
NP_011871.1

Gene-based displays