About the Aspergillus fumigatus genome
Seven centres collaborated to sequence and generate first-pass annotation of this genome: The Wellcome Trust Sanger Institute, The J. Craig Venter Institute (JCVI formerly known as TIGR), The University of Manchester, The Pasteur Institute, The University of Salamanca, Complutense University, and Centro de Investigaciones Biologicas. Many other experts then joined this group to manually refine the annotation and to perform analysis between A. fumigatus, A. nidulans and A. oryzae. The resultant genome was released in December 2005.
This genome was sequenced by the whole-genome random shotgun method, giving 10.5x coverage, and was refined by optical mapping. Closure was obtained by directed sequencing and manual editing. First-pass annotation was carried out by the JCVI pipeline 'Eukaryotic Genome Control'. The task of managing and directing further annotation of this genome was undertaken by The University of Manchester via JCVI's annotation system 'Manatee'. Several programs were also used by the Sanger Institute and TIGR to aid in the functional assignment of a predicted gene: i.e., NAP, BLASTP, InterProScan, HMM2, PrositeSearch, Psort, SignalP and TMHMM. Second-pass computational and manual annotation were carried out via the JCVI as part of an international comparative project in 2007.
Non coding RNA genes have been annotated using tRNAScan-SE (Lowe, T.M. and Eddy, S.R. 1997), RFAM (Griffiths-Jones et al 2005), and RNAmmer (Lagesen K.,et al 2007); additional analysis tools have also been applied.
This species currently has no variation database. However you can process your own variants using the Variant Effect Predictor: