Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation [Source:SGD;Acc:S000001049]
Chromosome VIII: 120,091-121,683 reverse strand.
This transcript has 1 exon, is annotated with 20 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YHR007C Show transcript tableHide transcript table
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ERG11 | YHR007C_mRNA | 1593 | 530aa | YHR007C | Protein coding | P10614 | NM_001179137.1 NP_011871.1 |