Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation [Source:SGD;Acc:S000001049]
CYP51
Chromosome VIII: 120,091-121,683 reverse strand.
R64-1-1:BK006934.2
This gene has 1 transcript (splice variant), 467 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
ERG11 | YHR007C_mRNA | 1593 | 530aa | YHR007C | Protein coding | P10614 | - | Ensembl Canonical, |