Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390]

Chromosome XII: 915,156-919,019 reverse strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 378 orthologues and 5 paralogues.

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