Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390]
Chromosome XII: 915,156-919,019 reverse strand.
R64-1-1:BK006945.2
This gene has 1 transcript (splice variant), 372 orthologues and 5 paralogues.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
SKI2 | YLR398C_mRNA | 3864 | 1287aa | YLR398C | Protein coding | P35207 | - | Ensembl Canonical, |