Ski complex component and putative RNA helicase; mediates 3'-5' RNA degradation by the cytoplasmic exosome; null mutants have superkiller phenotype of increased viral dsRNAs and are synthetic lethal with mutations in 5'-3' mRNA decay; mutations in the human ortholog, SKIV2L, causes Syndromic diarrhea/Trichohepatoenteric (SD/THE) syndrome [Source:SGD;Acc:S000004390]

Chromosome XII: 915,156-919,019 reverse strand.

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 41 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YLR398C Show transcript tableHide transcript table