Saccharomyces cerevisiae (R64-1-1)
Description

Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress [Source:SGD;Acc:S000001121]

Synonyms

ERN1

Location

Chromosome VIII: 258,244-261,591 reverse strand.

R64-1-1:BK006934.2

About this gene

This gene has 1 transcript (splice variant), 246 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
IRE1YHR079C_mRNA33481115aaYHR079C
 
Protein coding
P32361 NM_001179209.1
NP_011946.1

Gene-based displays