Flavin-dependent monooxygenase involved in ubiquinone biosynthesis; responsible for hydroxylation at position C5 and deamination at C4 during ubiquinone (Coenzyme Q) biosynthesis; localizes to matrix face of mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes; human homolog COQ6 can complement yeast null mutant and is implicated in steroid-resistant nephrotic syndrome (SRNS) [Source:SGD;Acc:S000003487]
Chromosome VII: 1,002,523-1,003,962 reverse strand.
R64-1-1:BK006941.2
This gene has 1 transcript (splice variant), 308 orthologues and is a member of 3 Ensembl protein families.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
COQ6 | YGR255C_mRNA | 1440 | 479aa | YGR255C | Protein coding | P53318 | NM_001181384.1 NP_011771.1 |