Saccharomyces cerevisiae (R64-1-1)

NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]


Chromosome IV: 1,213,904-1,214,842 forward strand.


About this gene

This gene has 1 transcript (splice variant), 621 orthologues and 13 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q12458 -Ensembl Canonical