NADPH-dependent aldo-keto reductase; reduces multiple substrates including 2-methylbutyraldehyde and D,L-glyceraldehyde, expression is induced by osmotic and oxidative stress; functionally redundant with other aldo-keto reductases; protein abundance increases in response to DNA replication stress; YPR1 has a paralog, GCY1, that arose from the whole genome duplication; human homolog AKR1B1 can complement yeast null mutant [Source:SGD;Acc:S000002776]
Chromosome IV: 1,213,904-1,214,842 forward strand.
This transcript has 1 exon, is annotated with 15 domains and features, is associated with 29 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDR368W Show transcript tableHide transcript table