Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins [Source:SGD;Acc:S000002550]

Location

Chromosome IV: 742,042-743,874 reverse strand.

R64-1-1:BK006938.2

About this gene

This gene has 1 transcript (splice variant), 58 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SAN1YDR143C_mRNA1833610aaYDR143C
 
Protein coding
P22470 NM_001180450.3
NP_010427.3

Gene-based displays