Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-protein ligase; involved in proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition; prefers a window of exposed hydrophobicity that causes a particular level of protein insolubility, suggesting that San1p evolved to target highly aggregation-prone proteins [Source:SGD;Acc:S000002550]

Location
About this transcript

This transcript has 1 exon, is annotated with 23 domains and features, is associated with 26 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YDR143C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
SAN1YDR143C_mRNA1833610aaYDR143C
 
Protein coding
P22470 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,833 bps, Translation length: 610 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P22470

Version

YDR143C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD