Saccharomyces cerevisiae (R64-1-1)
Description

Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex, which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; involved in localizing Ypt7p to the vacuolar membrane; required for macroautophagy, the CVT pathway and mitophagy [Source:SGD;Acc:S000000335]

Synonyms

CVT16

Location

Chromosome II: 497,163-499,277 forward strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 27 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CCZ1YBR131W_mRNA2115704aaYBR131W
 
Protein coding
P38273 NM_001178479.3
NP_009689.3

Gene-based displays