Subunit of a heterodimeric guanine nucleotide exchange factor (GEF); subunit of the Mon1-Ccz1 GEF complex, which stimulates nucleotide exchange and activation of Ypt7p, a Rab family GTPase involved in membrane tethering and fusion events at the late endosome and vacuole; GEF activity is stimulated by membrane association and anionic phospholipids; involved in localizing Ypt7p to the vacuolar membrane; required for macroautophagy, the CVT pathway and mitophagy [Source:SGD;Acc:S000000335]
Chromosome II: 497,163-499,277 forward strand.
This transcript has 1 exon, is annotated with 10 domains and features, is associated with 69 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YBR131W Show transcript tableHide transcript table