Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]

Chromosome II: 657,832-658,392 forward strand.

This transcript has 1 exon, is annotated with 20 domains and features, is associated with 34 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YBR217W Show transcript tableHide transcript table