Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation [Source:SGD;Acc:S000000421]

Synonyms

APG12

Location

Chromosome II: 657,832-658,392 forward strand.

R64-1-1:BK006936.2

About this gene

This gene has 1 transcript (splice variant), 215 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
ATG12YBR217W_mRNA561186aaYBR217W
 
Protein coding
P38316 NM_001178565.1
NP_009776.1

Gene-based displays