Saccharomyces cerevisiae (R64-1-1)
Description

Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3; mutants are defective in endocytosis, bud site selection, cytokinesis; human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency; human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches [Source:SGD;Acc:S000005707]

Location
About this transcript

This transcript has 1 exon, is annotated with 38 domains and features, is associated with 55 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YOR181W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
LAS17YOR181W_mRNA1902633aaYOR181W
 
Protein coding
Q12446 NM_001183600.1
NP_014824.1
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,902 bps, Translation length: 633 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q12446

Version

YOR181W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD

Transcript-based displays