Metalloendopeptidase of the mitochondrial inner membrane; important for adaptive responses to various homeostatic insults, preservation of normal mitochondrial function under damage-eliciting conditions, and stability of respiratory supercomplexes; involved in turnover of membrane-embedded proteins; mediates degradation of Cox1p in coa2 mutant cells; zebrafish ortholog has a role in organ development and mouse ortholog is also required for respiratory supercomplex stability [Source:SGD;Acc:S000001795]

Chromosome XI: 603,195-604,232 reverse strand.

This transcript has 1 exon, is annotated with 6 domains and features, is associated with 13 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKR087C Show transcript tableHide transcript table