Protein involved in Fe-S cluster transfer to mitochondrial clients; protects [4Fe-4S] clusters from damage due to oxidative stress; acts along with Bol3 at a late step in the transfer of [4Fe-4S] clusters from the ISA complex to client proteins; Fe-S loaded homodimer at steady state; similar to NifU, a bacterial protein required for Fe/S cluster maturation; ortholog of the human NFU1, mutations of which are associated with Multiple Mitochondria Dysfunctions Syndrome (MMDS1) [Source:SGD;Acc:S000001523]

Chromosome XI: 361,058-361,828 reverse strand.

This transcript has 1 exon, is annotated with 13 domains and features, is associated with 35 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YKL040C Show transcript tableHide transcript table