Saccharomyces cerevisiae (R64-1-1)
Description

3'-5' DNA helicase involved in error-free bypass of DNA lesions; binds flap DNA, stimulates activity of Rad27p and Dna2p; prevents crossovers between ectopic sequences by removing substrates for Mus81-Mms4 or Rad1-Rad10 cleavage; homolog of human FANCM Fanconi anemia protein that is involved in stabilizing and remodeling blocked replication forks; member of SF2 DExD/H superfamily of helicases; nonsense or missense mutations in FANCM can make people more likely to get cancer [Source:SGD;Acc:S000001441]

Location
About this transcript

This transcript has 1 exon, is annotated with 24 domains and features, is associated with 56 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YIR002C Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
MPH1YIR002C_mRNA2982993aaYIR002C
 
Protein coding
P40562 -Ensembl Canonical
Statistics

Exons: 1, Coding exons: 1, Transcript length: 2,982 bps, Translation length: 993 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: P40562

Version

YIR002C_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD