Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation [Source:SGD;Acc:S000002459]
Chromosome IV: 558,511-560,625 reverse strand.
This transcript has 1 exon, is annotated with 15 domains and features, is associated with 30 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YDR052C Show transcript tableHide transcript table