Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation [Source:SGD;Acc:S000002459]

DNA52, LSD7

Chromosome IV: 558,511-560,625 reverse strand.

R64-1-1:BK006938.2

This gene has 1 transcript (splice variant) and 308 orthologues.

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