3'-5' DNA helicase involved in error-free bypass of DNA lesions; binds flap DNA, stimulates activity of Rad27p and Dna2p; prevents crossovers between ectopic sequences by removing substrates for Mus81-Mms4 or Rad1-Rad10 cleavage; homolog of human FANCM Fanconi anemia protein that is involved in stabilizing and remodeling blocked replication forks; member of SF2 DExD/H superfamily of helicases; nonsense or missense mutations in FANCM can make people more likely to get cancer [Source:SGD;Acc:S000001441]
Chromosome IX: 357,415-360,396 reverse strand.
This transcript has 1 exon, is annotated with 24 domains and features, is associated with 56 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YIR002C Show transcript tableHide transcript table