Scaffold protein involved in the formation of early endocytic sites; putative regulator of cytokinesis; homo-oligomerization is required for localization to and organization of endocytic sites; has a network of interactions with other endocytic proteins; binds membranes in a ubiquitin-dependent manner; may also bind ubiquitinated membrane-associated proteins; interacts with Cmk2 and functions upstream of CMK2 in regulating non-apoptotic cell death; homolog of mammalian Eps15 [Source:SGD;Acc:S000000143]

Chromosome II: 127,895-132,040 reverse strand.

This transcript has 1 exon, is annotated with 57 domains and features, is associated with 69 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YBL047C Show transcript tableHide transcript table