Endosomal protein involved in turnover of plasma membrane proteins; member of the DUP380 subfamily of conserved, often subtelomeric COS genes; required for the multivesicular vesicle body sorting pathway that internalizes plasma membrane proteins for degradation; Cos proteins provide ubiquitin in trans for nonubiquitinated cargo proteins [Source:SGD;Acc:S000001702]

Chromosome XI: 14,485-15,708 forward strand.

This transcript has 1 exon, is annotated with 9 domains and features, is associated with 68 variant alleles and maps to 43 oligo probes.

This transcript is a product of gene YKL219W Show transcript tableHide transcript table