Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant [Source:SGD;Acc:S000006344]

Chromosome XVI: 814,391-815,536 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 220 orthologues and is a member of 2 Ensembl protein families.

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