Lyso-phosphatidylcholine acyltransferase; required for normal phospholipid content of mitochondrial membranes; major determinant of the final acyl chain composition of the mitochondrial-specific phospholipid cardiolipin; mutations in human ortholog tafazzin (TAZ) cause Barth syndrome, a rare X-linked disease characterized by skeletal and cardiomyopathy and bouts of cyclic neutropenia; a specific splice variant of human TAZ can complement yeast null mutant [Source:SGD;Acc:S000006344]

Chromosome XVI: 814,391-815,536 forward strand.

This transcript has 1 exon, is annotated with 11 domains and features, is associated with 15 variant alleles and maps to 29 oligo probes.

This transcript is a product of gene YPR140W Show transcript tableHide transcript table