Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269]

REO1

Chromosome XVI: 679,693-680,799 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 183 orthologues and is a member of 2 Ensembl protein families.

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