Heme-dependent repressor of hypoxic genes; mediates aerobic transcriptional repression of hypoxia induced genes such as COX5b and CYC7; repressor function regulated through decreased promoter occupancy in response to oxidative stress; contains an HMG domain that is responsible for DNA bending activity; involved in the hyperosmotic stress resistance [Source:SGD;Acc:S000006269]
REO1
Chromosome XVI: 679,693-680,799 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant) and 32 orthologues.