Glutamine synthetase (GS); synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation; forms filaments of back-to-back stacks of cylindrical homo-decamers at low pH, leading to enzymatic inactivation and storage during states of advanced cellular starvation; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress [Source:SGD;Acc:S000006239]
Chromosome XVI: 642,208-643,320 forward strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 183 orthologues and is a member of 1 Ensembl protein family.