Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006098]

Chromosome XVI: 213,042-213,962 reverse strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 16 orthologues and 1 paralogue.

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