Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006098]
Chromosome XVI: 213,042-213,962 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 17 orthologues and 1 paralogue.
Name | Transcript ID | bp | Protein | Translation ID | Biotype | UniProt | RefSeq | Flags |
---|---|---|---|---|---|---|---|---|
CUP9 | YPL177C_mRNA | 921 | 306aa | YPL177C | Protein coding | P41817 | - | Ensembl Canonical, |