Homeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000006098]
Chromosome XVI: 213,042-213,962 reverse strand.
R64-1-1:BK006949.2
This gene has 1 transcript (splice variant), 17 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.