Saccharomyces cerevisiae (R64-1-1)

Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease [Source:SGD;Acc:S000006017]


Chromosome XVI: 366,927-368,018 forward strand.


About this gene

This gene has 1 transcript (splice variant) and 144 orthologues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
Q02890 -Ensembl Canonical