Conserved peptide N-glycanase; deglycosylating enzyme that cleaves N-glycans that are attached to misfolded ERAD substrate glycoproteins prior to proteasome-dependent degradation; localizes to the cytoplasm and nucleus; activity is enhanced by interaction with Rad23p; human ortholog NGLY1 is associated with a syndrome characterized by developmental delays, epilepsy, absence of tears and liver disease [Source:SGD;Acc:S000006017]

Chromosome XVI: 366,927-368,018 forward strand.

R64-1-1:BK006949.2

This gene has 1 transcript (splice variant), 144 orthologues and is a member of 1 Ensembl protein family.

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