Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]

ART1

Chromosome XV: 918,606-921,062 reverse strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 334 orthologues and is a member of 2 Ensembl protein families.

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