Saccharomyces cerevisiae (R64-1-1)
Description

Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]

Synonyms

ART1

Location

Chromosome XV: 918,606-921,062 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 334 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
LDB19YOR322C_mRNA2457818aaYOR322C
 
Protein coding
Q12502 NM_001183742.3
NP_014967.3

Gene-based displays