Alpha-arrestin involved in ubiquitin-dependent endocytosis; regulates endocytosis of plasma membrane proteins by recruiting the ubiquitin ligase Rsp5p to its targets; involved in the basal internalization and turnover of alpha-factor receptor Ste2p; recruits ubiquitin ligase Rsp5p to Ste2p via its 2 PPXY motifs; inhibited by Npr1p-mediated phosphorylation, which affects translocation between the cytosol and the plasma membrane [Source:SGD;Acc:S000005849]
Chromosome XV: 918,606-921,062 reverse strand.
This transcript has 1 exon, is annotated with 15 domains and features, is associated with 36 variant alleles and maps to 29 oligo probes.
This transcript is a product of gene YOR322C Show transcript tableHide transcript table