Saccharomyces cerevisiae (R64-1-1)

Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase; required for biosynthesis of isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; also has a role in tRNA gene-mediated silencing; gene encodes two isozymic forms; converts to a prion form, prion conversion contributes to azole antifungal resistance by upregulating ergosterol biosynthesis; homolog of human TRIT1, a mutation in which is associated with severe combined respiratory chain defects [Source:SGD;Acc:S000005800]


Chromosome XV: 837,674-838,960 forward strand.


About this gene

This gene has 1 transcript (splice variant), 226 orthologues and is a member of 3 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P07884 NM_001183693.3

Gene-based displays