Saccharomyces cerevisiae (R64-1-1)
Description

Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]

Synonyms

KAT5, TAS1

Location

Chromosome XV: 792,531-793,868 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 202 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
ESA1YOR244W_mRNA1338445aaYOR244W
 
Protein coding
Q08649 NM_001183663.3
NP_014887.3

Gene-based displays