Saccharomyces cerevisiae (R64-1-1)
Description

Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]

Location
About this transcript

This transcript has 1 exon, is annotated with 18 domains and features, is associated with 21 variant alleles and maps to 29 oligo probes.

Gene

This transcript is a product of gene YOR244W Show transcript tableHide transcript table

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
ESA1YOR244W_mRNA1338445aaYOR244W
 
Protein coding
Q08649 NM_001183663.3
NP_014887.3
Statistics

Exons: 1, Coding exons: 1, Transcript length: 1,338 bps, Translation length: 445 residues

Uniprot

This transcript corresponds to the following Uniprot identifiers: Q08649

Version

YOR244W_mRNA

Type

Protein coding

Annotation Method

Annotation imported from SGD

Transcript-based displays