Catalytic subunit of the histone acetyltransferase complex (NuA4); acetylates four conserved internal lysines of histone H4 N-terminal tail and can acetylate histone H2A; master regulator of cellular acetylation balance; required for cell cycle progression and transcriptional silencing at the rDNA locus and regulation of autophagy; human ortholog TIP60/KAT5 is implicated in cancer and other diseases, functionally complements lethality of the esa1 null mutation [Source:SGD;Acc:S000005770]

KAT5, TAS1

Chromosome XV: 792,531-793,868 forward strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 225 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.

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