Saccharomyces cerevisiae (R64-1-1)
Description

Actin assembly factor; C-terminal WCA domain activates Arp2/3 complex-mediated nucleation of branched actin filaments, polyproline domain nucleates actin filaments independent of Arp2/3; mutants are defective in endocytosis, bud site selection, cytokinesis; human homolog WAS (Wiskott-Aldrich Syndrome) implicated in severe immunodeficiency; human WAS complements yeast null mutant, but only in presence of WIPF1, which mediates localization of WAS to cortical patches [Source:SGD;Acc:S000005707]

Synonyms

BEE1

Location

Chromosome XV: 675,939-677,840 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 297 orthologues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
LAS17YOR181W_mRNA1902633aaYOR181W
 
Protein coding
Q12446 NM_001183600.1
NP_014824.1

Gene-based displays