Saccharomyces cerevisiae (R64-1-1)
Description

Lipid-binding ER protein involved in ER-plasma membrane tethering; one of 6 proteins (Ist2p, Scs2p, Scs22p, Tcb1p, Tcb2p, Tcb3p) that connect ER to plasma membrane and regulate PI4P levels by controlling access of Sac1p phosphatase to its substrate PI4P in PM; contains 3 calcium and lipid binding domains; non-tagged protein also localizes to mitochondria; C-termini of Tcb1p, Tcb2p and Tcb3p interact; TCB1 has a paralog, TCB2, that arose from the whole genome duplication [Source:SGD;Acc:S000005612]

Location

Chromosome XV: 483,219-486,779 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 304 orthologues, 2 paralogues and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
TCB1YOR086C_mRNA35611186aaYOR086C
 
Protein coding
Q12466 NM_001183505.1
NP_014729.1

Gene-based displays