Saccharomyces cerevisiae (R64-1-1)
Description

Ubiquitin-binding protein; functions as ubiquitin-Atg8p adaptor in ubiquitin-dependent autophagy; serves as proteaphagy receptor for inactivated 26S proteasomes; contains CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; CUE5 has a paralog, DON1, that arose from the whole genome duplication; human TOLLIP is a functional CUE-domain homolog, can complement yeast null mutant, rescuing hypersensitivity of cue5 null mutant cells to Htt-96Q [Source:SGD;Acc:S000005568]

Location

Chromosome XV: 408,425-409,660 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 306 orthologues and is a member of 1 Ensembl protein family.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
CUE5YOR042W_mRNA1236411aaYOR042W
 
Protein coding
Q08412 NM_001183461.1
NP_014685.1

Gene-based displays