DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome [Source:SGD;Acc:S000005531]

LIG4

Chromosome XV: 334,509-337,343 reverse strand.

R64-1-1:BK006948.2

This gene has 1 transcript (splice variant), 326 orthologues, 1 paralogue and is a member of 1 Ensembl protein family.

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