Saccharomyces cerevisiae (R64-1-1)
Description

DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome [Source:SGD;Acc:S000005531]

Gene Synonyms

LIG4

Location

Chromosome XV: 334,509-337,343 reverse strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 326 orthologues and 1 paralogue.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
DNL4YOR005C_mRNA2835944aaYOR005C
 
Protein coding
Q08387 -Ensembl Canonical