Saccharomyces cerevisiae (R64-1-1)
Description

RING-H2 domain core subunit of multiple ubiquitin ligase complexes; subunit of Skp1-Cullin-F-box (SCF) that tethers the Cdc34p (E2) and Cdc53p (cullin) SCF subunits, and is required for degradation of Gic2p, Far1p, Sic1p and Cln2p; subunit of the Rtt101p-Mms1p-Mms22p ubiquitin ligase that stabilizes replication forks after DNA lesions; subunit of the Cul3p-Elc1p-Ela1p ubiquitin ligase involved in Rpb1p degradation as part of transcription-coupled repair [Source:SGD;Acc:S000005493]

Synonyms

HRT2, RBX1, ROC1

Location

Chromosome XV: 70,325-70,690 forward strand.

R64-1-1:BK006948.2

About this gene

This gene has 1 transcript (splice variant), 219 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
HRT1YOL133W_mRNA366121aaYOL133W
 
Protein coding
Q08273 NM_001183387.1
NP_014508.1

Gene-based displays