Saccharomyces cerevisiae (R64-1-1)

Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication [Source:SGD;Acc:S000004490]

Gene Synonyms

cTPxI, TPX1, ZRG14


Chromosome XIII: 220,138-220,728 forward strand.


About this gene

This gene has 1 transcript (splice variant), 277 orthologues and 2 paralogues.

NameTranscript IDbpProteinTranslation IDBiotypeUniProtRefSeqFlags
Protein coding
P34760 -Ensembl Canonical