Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication [Source:SGD;Acc:S000004490]

cTPxI, TPX1, ZRG14

Chromosome XIII: 220,138-220,728 forward strand.

R64-1-1:BK006946.2

This gene has 1 transcript (splice variant), 277 orthologues and 2 paralogues.

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