Thioredoxin peroxidase; acts as both ribosome-associated and free cytoplasmic antioxidant; self-associates to form high-molecular weight chaperone complex under oxidative stress; chaperone activity essential for growth in zinc deficiency; required for telomere length maintenance; binds and modulates Cdc19p activity; protein abundance increases, forms cytoplasmic foci during DNA replication stress; TSA1 has a paralog, TSA2, that arose from the whole genome duplication [Source:SGD;Acc:S000004490]
cTPxI, TPX1, ZRG14
Chromosome XIII: 220,138-220,728 forward strand.
R64-1-1:BK006946.2
This gene has 1 transcript (splice variant), 277 orthologues, 2 paralogues and is a member of 1 Ensembl protein family.