Signal transducing MEK kinase; involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p; protein abundance increases in response to DNA replication stress [Source:SGD;Acc:S000004354]

Chromosome XII: 849,866-852,019 forward strand.

R64-1-1:BK006945.2

This gene has 1 transcript (splice variant), 241 orthologues, 1 paralogue and is a member of 2 Ensembl protein families.

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